This is a rendering of the "Toaster House" designed by Tempietto Homes. It features panelized, energy efficient construction and a rather unique, perhaps Venturiesque, floor plan with modern detailing.
Pre-fabricated architecture offers theoretical advantages and has been touted as far back as the late 1800's. Even before that, many timberframe buildings, including tythe barns in England, featured shop built structural systems. The nadir of pre-fab was put on display following Hurricane Katrina, when thousands of FEMA trailers proved to be practically uninhabitable.
I was educated in the stick-built lumber tradition and I have a bias towards it as an assembly method. The geometric possibilities are less constrained and the efficiencies that can be realized with on-site construction are highly competitive--particularly since the factory space has no overhead associated with it.